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Cardiovascular/Pulmonary: Case 3

D. Dows and M. Heart

Weeks 2 & 3 - July 3-6

Boards and Beyond - Required

Supplementary Harrison's Pathophysiology Videos

Short animations from Harrison's

Total Time: 5 min 40 sec

Enrichment 19

Weekly Objectives

CAD, Cardiac Ischemia, Unstable Angina, Stable Angina, and ST-Elevation Myocardial Infarction (STEMI)

Coronary Artery Disease
  1. Explain the pathophsyiology of stable coronary arterty disease.
  2. List the risk factors for development of coronary artery disease.
  3. Describe the mechanism of injury to the arterial endothelium which represents a primary event in atherogenesis.
  4. Describe the cholesterol homeostasis and reverse cholesterol transport.
  5. Utilize the proper testing(s) for diagnosis of coronary artery disease. 
  6. Calculate sensitivity and specificity, positive predictive value (PPV), and negative predictive value (NPV) of testing used for diagnosis.
  7. Apply sensitivity and specificity, PPV and NPV of testing in coronary artery disease evaluation. 
  8. Recognize the ischemic cascade and its relation to diagnostic testings. 
  9. Select treatment of stable coronary artery disease, medical treatment and revascularization (percutaneous coronary intervention (PCI) or surgical). 
Acute Coronary Artery Syndrome
  1. Review the pathophysiology of the acute coronary syndromes 
  2. Manage the patient presenting with acute coronary syndrome, diagnosis and initial therapy.
  3. Review the different causes of elevated troponin. 
  4. Select the definitive therapy for acute coronary syndromes [percutaneous coronary intervention (PCI), thrombolytic therapy, etc.]
  5. Recognize the complications of acute myocardial infarction.
Unstable Angina
  1. Describe the pathophysiology and clinical manifestations of cardiac ischemia.
  2. Describe the types and gender specific differences in the clinical presentations of angina.
  3. Describe the pathology of stable versus unstable angina.
  4. Discuss the differential diagnoses of stable versus unstable angina.
  1. Describe the clinical presentation of a STEMI. 
  2. Differentiate between between STEMI vs NSTEMI vs stable CAD in terms of pathophysiology.
  3. Describe the mechanical complications of MI.
  4. Select pharmacological treatments and understand the mechanisms, side effects and interactions between drugs (if any).