Sub: Biomedical Importance; Membranes are Complex Structures Composed of Lipids, Proteins, & Carbohydrate-containing Molecules; Membrane Selectivity Allows Adjustments of Cell Composition & Function through Transport of Glucose Involves Several Mechanisms; Gap Junctions Allow Direct Flow of Molecules from One Cell to Another;
Sub: Cells Transport Certain Macromolecules Across the Plasma Membrane by Endocytosis & Exocytosis through Extracellular Vesicles (Exosomes) Represent a Novel, & Previously Underappreciated Mechanism of Cell-Cell Communication
Sub: Many Proteins Are Targeted by Signal Sequences to Their Correct Destinations; The Cytosolic Protein Sorting Branch Directs Proteins to Subcellular Organelles; Proteins Follow Several Routes to be Inserted into or Attached to the Membranes of the Endoplasmic Reticulum through Transport Vesicles Are Key Players in Intracellular Protein Traffic
Cheng PC, Alexiou S, Rubenstein RC. Safety and efficacy of treatment with lumacaftor in combination with ivacaftor in younger patients with cystic fibrosis. Expert Rev Respir Med. 2019;13(5):417-423. doi:10.1080/17476348.2019.1602040
Bacalhau M, Camargo M, Magalhães-Ghiotto GAV, Drumond S, Castelletti CHM, Lopes-Pacheco M. Elexacaftor-Tezacaftor-Ivacaftor: A Life-Changing Triple Combination of CFTR Modulator Drugs for Cystic Fibrosis. Pharmaceuticals (Basel). 2023;16(3):410. Published 2023 Mar 8. doi:10.3390/ph16030410