Guides: Pathobiology and Host Defense: Week 8

Pathology

Required - Robbins and Cotran Pathologic Basis of Disease - "Big Robbins"

Required - Robbins Basic Pathology - "Baby Robbins"

Sepsis: Inflammation Is a Necessary Evil
Nedeva C, Menassa J, Puthalakath H. Sepsis: Inflammation Is a Necessary Evil. Front Cell Dev Biol. 2019;7:108. Published 2019 Jun 20. doi:10.3389/fcell.2019.00108
Sepsis - Clinical Overview
Sepsis Fact Sheet - Sepsis Alliance
Sepsis Information Guides - Scroll to find the topic listed below
Sepsis and Antibiotic Resistance (left hand column)
Sepsis and ARDS (right hand column)
Sepsis and Bacterial Infections (left hand column)
Shock section of Ch 4 Hemodynamic Disorders, Thromboembolic Disease, and Shock IN: Robbins and Cotran Pathologic Basis of Disease

Recommended but not required supplements:

General review of course materials from weeks 1-3 and 5-7 in the context of sepsis

Sepsis and septic shock
Cecconi M, Evans L, Levy M, Rhodes A. Sepsis and septic shock. Lancet. 2018;392(10141):75-87. doi:10.1016/S0140-6736(18)30696-2
Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Shankar-Hari M, Phillips GS, Levy ML, et al. Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):775-787. doi:10.1001/jama.2016.0289
Ch 3 Inflammation and Repair IN: Robbins and Cotran Pathologic Basis of Disease
pages 71-113